Track record since I began my scientific career. The join of effort of the research group aims to expand our knowledge about Caspase function, and consequently the list of original publications.


Caspase-dependent activation of Hedgehog-signalling sustains proliferation and differentiation of ovarian somatic stem cells.

Alessia Galasso, Daria Iakovleva, LA. Baena-Lopez. BioRxiv. 2019 August. doi: 


Non-apoptotic caspase-dependent regulation of enteroblast quiescence in Drosophila

Lewis Arthurton, Dominik Antoni Nahotko, Jana Alonso, Luis Alberto Baena-Lopez

bioRxiv 707380; doi:


Lessons in genome engineering: opportunities, tools and pitfalls

Ingrid Poernbacher, Sam Crossman, Joachim Kurth, Hisashi Nojima, Alberto Baena-Lopez, Cyrille Alexandre, Jean-Paul Vincent

bioRxiv 710871; doi:


Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells

Baena-Lopez LA,  Arthurton L, Bischoff M, Vincent JP, Alexandre C, McGregor R. Development. 2018 December 2018 145: dev170811 doi: 10.1242/dev.170811

Learning on the fly: The interplay between Caspases and Cancer

Xu DC, Arthurton LBaena-Lopez LA. Biomed. Research International. 2018 March 14. [Epub ahead of print] 

All about the caspase-dependent functions without cell death.

Baena-Lopez LA. Semin Cell Dev Biol. 2018 Jan 20. [Epub ahead of print] 


Non-apoptotic Caspase regulation of stem cell properties.

Baena-Lopez LA, Arthurton L, Xu DC, Galasso A.

Semin Cell Dev Biol. 2017 Nov 1. [Epub ahead of print]



Patterning and growth control by membrane-tethered Wingless.

Alexandre C, Baena-Lopez A, Vincent JP.

Nature. 2014 Jan 9;505(7482):180-5. doi: 10.1038/nature12879. Epub 2013 Dec 25.




Accelerated homologous recombination and subsequent genome modification in Drosophila.

Baena-Lopez LA, Alexandre C, Mitchell A, Pasakarnis L, Vincent JP.

Development. 2013 Dec;140(23):4818-25. doi: 10.1242/dev.100933. Epub 2013 Oct 23.


Mechanisms and mechanics of cell competition in epithelia.

Vincent JP, Fletcher AG, Baena-Lopez LA.

Nat Rev Mol Cell Biol. 2013 Sep;14(9):581-91. doi: 10.1038/nrm3639. Epub 2013 Aug 14. Review.




Integration of morphogen signalling within the growth regulatory network.

Baena-Lopez LA, Nojima H, Vincent JP.

Curr Opin Cell Biol. 2012 Apr;24(2):166-72. doi: 10.1016/ Epub 2012 Jan 16. Review.




dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells.

Ziosi M, Baena-López LA, Grifoni D, Froldi F, Pession A, Garoia F, Trotta V, Bellosta P, Cavicchi S, Pession A.

PLoS Genet. 2010 Sep 23;6(9):e1001140. doi: 10.1371/journal.pgen.1001140.




Wingless promotes proliferative growth in a gradient-independent manner.

Baena-Lopez LA, Franch-Marro X, Vincent JP.

Sci Signal. 2009 Oct 6;2(91):ra60. doi: 10.1126/scisignal.2000360.


Characterization of the interface between normal and transformed epithelial cells.

Hogan C, Dupré-Crochet S, Norman M, Kajita M, Zimmermann C, Pelling AE, Piddini E, Baena-López LA, Vincent JP, Itoh Y, Hosoya H, Pichaud F, Fujita Y.

Nat Cell Biol. 2009 Apr;11(4):460-7. doi: 10.1038/ncb1853. Epub 2009 Mar 15.




Upregulation of glypicans in Hippo mutants alters the coordinated activity of morphogens.

Rodríguez I, Baena-Lopez LA, Baonza A.

Fly (Austin). 2008 Nov-Dec;2(6):320-2. Epub 2008 Nov 21.


The tumor suppressor genes dachsous and fat modulate different signalling pathways by regulating dally and dally-like.

Baena-Lopez LA, Rodríguez I, Baonza A.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9645-50. doi: 10.1073/pnas.0803747105. Epub 2008 Jul 9.


The expression of heat shock protein HSP60A reveals a dynamic mitochondrial pattern in Drosophila melanogaster embryos.

Baena-López LA, Alonso J, Rodriguez J, Santarén JF.

J Proteome Res. 2008 Jul;7(7):2780-8. doi: 10.1021/pr800006x. Epub 2008 Jun 13.


Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex.

Franch-Marro X, Wendler F, Guidato S, Griffith J, Baena-Lopez A, Itasaki N, Maurice MM, Vincent JP.

Nat Cell Biol. 2008 Feb;10(2):170-7. doi: 10.1038/ncb1678. Epub 2008 Jan 13.




Control of growth and positional information by the graded vestigial expression pattern in the wing of Drosophila melanogaster.

Baena-Lopez LA, García-Bellido A.

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13734-9. Epub 2006 Sep 1.




Characterization of the Drosophila melanogaster mitochondrial proteome.

Alonso J, Rodriguez JM, Baena-López LA, Santarén JF.

J Proteome Res. 2005 Sep-Oct;4(5):1636-45.


The orientation of cell divisions determines the shape of Drosophila organs.

Baena-López LA, Baonza A, García-Bellido A.

Curr Biol. 2005 Sep 20;15(18):1640-4.


Constitutive expression of heat shock protein p23 correlates with proneural territories in imaginal discs of Drosophila melanogaster.

Alonso J, Rodriguez JM, Baena-López LA, Alonso MT, Santarén JF.

Proteomics. 2005 Sep;5(14):3604-13.




Wg and Egfr signalling antagonise the development of the peripodial epithelium in Drosophila wing discs.

Baena-López LA, Pastor-Pareja JC, Resino J.

Development. 2003 Dec;130(26):6497-506.


Genetic requirements of vestigial in the regulation of Drosophila wing development.

Baena-López LA, García-Bellido A.

Development. 2003 Jan;130(1):197-208.

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